How Donor And Recipient are Selected

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How Donor And Recipient are Selected

Postby admin on Sun Jan 18, 2009 10:27 am

How a kidney donor is selected in kidney foundation

The following relationship with patient is evaluated first.

| The Relationship is a must : -

• Parent to sibling
• Sibling to sibling
• Maternal and paternal uncle/Aunty
• Spouse to spouse

| Age-Between 18-65 years age

| Blood Group :

• 'O' for Universal donor
• AB for Universal recipient
• A and B similar with donor & recipient

The following disease are excluded from donor

• Diabetes, Hypertension, kidney disease,systemic disease affecting kidney,cancer :


The Kidney function and other test of donor must be normal :

| eGFR > 75 ml sqm/min

| UTP < 250 mg/ day

| HbsAg, Anti HCV, HIV, VDRL-all negative

| CMV- negative

Tissue Type : Should be done in all cases :
| At least 25% match with recipient. Cross match negative including

| T cell and B cell.

| Renal C-T angiogram..

| ECG/X-ray chest/other as & when necessary.



How a recipient is selected :

The recipient must be End Stage Kidney Disease
• Age -12 to 60 years age

The Cause of ESRD to be evaluated for recipient :

The following diseases are contra-indicated for transplant :

• Obstructive Uropathy
• Neurogenic bladder
• Accelerated Hypertension
• Acute myocardial infarction
• Severe left ventricular dysfunction
• Atherosclerotic changes in medium and great vessels
• Cancer
• Chronic infection
• Rapidly progressive GN of recent onset
• Active tuberculosis
• Active CMV infection.

| Preparation for a recipient :

• Physical fitness
• Control of Hypertension and diabetes
• Control of infection
• HbsAg, HCV, HIV, VDRL-negative
• Blood group/tissue type
• Psychiatric assessment
• Social assessment
• Economic condition.

| How a Kidney Recipient is prepared :

• eGFR- ? 15 ml-Preparation for RRT to be started
• Cause of ESRD-.
• A-V fistula constructed
• Monthly monitoring of renal function test.
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